Can I take omeprazole with Voriconazole

Omeprazole oral and Voriconazole oral Drug Interactions

Voriconazole gets metabolized by CYP 2C19. That’s why patient on Omeprazole will get increased blood levels of Voriconazole than patients without Omeprazole. Dose adjustments are required when patient is taking Omeprazole to control Zollinger-Ellison syndrome or in any case patient is taking more than 40 mg per day. While treating someone with Voriconazole, keep Omeprazole at 20 mg daily, or lower.

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